Taking Synofit when you have gallstones

Be careful while taking Synofit when you have large gallstones.
In the instructions for Synofit Premium we have included the following warning:

Please note! Not suitable for people allergic to molluscan shellfish. Although some users allergic to molluscan shellfish have experienced no ill effects from using Synofit, we still recommend not to use Synofit if you are allergic to molluscan shellfish. Not for children. Do not use during pregnancy. Do not use if you have large gallstones. Do not use if the packaging is damaged or if the product is past its expiration date. This date, which is printed on the bottle and blister, indicates when the product can no longer be guaranteed to be of the highest quality. For the follow-up treatment, the pack size 400 ml is not suitable, because of the limited shelf life after opening.

What is the reason for that warning

Synofit Premium contains Curcumin that can have a slight stimulating effect on the contractions of the gallbladder. In fact, under normal circumstances that is a healthy effect since a slight stimulation of the contractions of the gallbladder can help to prevent the formation of gallbladder stones. However, when there are already large gallbladder stones present, then these slight contractions can result in discomfort. At this moment we have received information that this has happened twice amongst users of Synofit.
In both cases, the complaints stopped immediately after these two persons stopped taking Synofit. Even though only a small minority of the people who have gallstones will notice complaints when they take Synofit we advise them not to take Synofit.

How do I know whether I have gallstones?

Usually, large gallstones do not cause a lot of discomfort. Often people do not know that they have them and they are accidentally discovered when a routine echo is made of the belly. Even when they are discovered, often they are not removed by treatment unless they cause a lot of discomfort. Small gallstones are usually more discomfort since they can lead to irritation or even obstruction of the gall ducts. When that is the case they are usually treated and removed.

What if my gallbladder has already been removed?

When you do not have a gallbladder anymore, Curcumin cannot have an influence on the gallbladder contractions. Some people can still have complaints from little gallstones in the remaining ducts after the gallbladder has been removed. It is unknown whether Curcumin has any influence on such complaints. When you take Synofit while you already have such complaints, we advise you to be alert and to stop taking Synofit when the gallbladder discomfort increases.